Site-directed mutagenesis of the P2 residue of human antithrombin
نویسندگان
چکیده
منابع مشابه
Suggestions for "safe" residue substitutions in site-directed mutagenesis.
The conserved topological structure observed in various molecular families such as globins or cytochromes c allows structural equivalencing of residues in every homologous structure and defines in a coherent way a global alignment in each sequence family. A search was performed for equivalent residue pairs in various topological families that were buried in protein cores or exposed at the prote...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1994
ISSN: 0014-5793
DOI: 10.1016/0014-5793(94)80403-6